OZISET 500

OZISET-500 Tablets
Azithromycin 500 mg Tabs.

Azithromycin is an azalide, a subclass of macrolide antibiotics. Azithromycin acts by binding to the 50S
ribosomal subunit of susceptible microorganisms and, thus, interfering with microbial protein synthesis.

INDICATIONS

Oziset is indicated in the treatment of:
->Upper respiratory tract infections (including ear, nose and throat infections): Tonsillitis, sinusitis, otitis
media and pharyngitis.
-> Lower respiratory tract infections: Community acquired pneumonias, acute bacterial exacerbations of
chronic bronchitis, chronic obstructive pulmonary disease, bronchitis due to Haemophilus influenzae,
Moraxella catarrhalis or Streptococcus pneumoniae.
-> Genitourinary tract infections (including sexually transmitted diseases): Urethritis, prostatitis, cervicitis,
cervico-vaginitis and salpingitis due to N. gonorrhoeae and C. trachomatis. Genital ulcer disease
(chanchroid) in men due to Haemophilus ducreyi.
-> Skin and skin structure infections: Folliculitis, furuncles, carbuncles, impetigo, pyoderma, infected ulcer,
infected dermatitis, cellulitis and erysipelas due to S. aureus, S. pyogenes or S. agalactiae.

OTHER INDICATIONS:

-> Prophylaxis and treatment of malaria.
-> Treatment of acne.
-> Treatment of chlamydial conjunctivitis.

DOSAGE AND ADMINISTRATION

Adults

500 mg as a single dose on the first day followed by 250 mg once daily on days 2 to 5 for a total dose of 1.5 gm
or 500 mg once daily for 3 days.
Sexually transmitted diseases: Gonorrhoea: 2 gm as a stat dose Chancroid: 1 gm as a stat dose Non-
gonococcal urethritis and cervicitis due to C. trachomatis —1 gm as a stat dose Syphilis: 1 gm o.d. for 5 days or
500 mg o.d. for 10 days.

Malaria: Prophylaxis:
500 mg on first day followed by 250 mg/day for 7 days. Treatment: 1000-1500 mg once daily for 3 days with usual doses of chloroquine.

Acne:
250-500 mg on 3 consecutive days in a week for 12 weeks.

Children under 16 years

The usual dose for children is 10 mg/kg body weight orally, once a day for 3 days. Alternatively after a 10
mg/kg body weight oral loading dose on the first day, therapy can be continued at a dose of 5 mg/kg body
weight on subsequent four days.

ronchitis t CAP — Community acquired pneumonia t UTIs — Urinary tract infections § SSSIs — Skin and
skin structure infections tt MDR-TB — Multi-drug resistant tuberculosis

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