MORTRIP -PLUS

MORTRIP -PLUS Tablets
Aceclofenac 100mg + Paracetamol 325mg + Trypsin Chymotripsin 100000 Armour Units

TROMITRIP contains proteolytic enzymes — Trypsin & Chymotrypsin.
These have been used widely, with significant clinical success in the management of major trauma & ucJnd
healing, and in reducing the healing time.

HIGHLIGHTS (USPs)
-> Reduces – edema, hematoma and inflammation
-> Restores microcirculation
-> Enhances phagocytosis
-> Minimizes necrosis and scar formation
-> Possibly enhances penetration of co-prescribed antibiotics
-> Shortens recovery time by 50%

CLINICAL PHARMACOLOGY

a. Fibrinolytic

When fibrin clots have stopped bleeding, body’s own fibrinolytic agent — PLASMIN breaks the fibrin barrier.
Liver, in response to trauma, releases APR’s (Acute Phase Reactants) that inhibits Plasmin (and its fibrinolytic
action). Breaking of fibrin barrier improves and restores circulation, resolving edema, hematoma and pain,
promoting phagocytosis to remove the debris an accelerate recovery.

b. Vascular response modulator

On administering Trypsin Chymotripsin, there is increase in levels of APR’s, which are known to inhibit
‘necrotic’ damage caused by proteases (Neutrophil elastase & Cathepsin G) thus minimizing necrotic damage
and scarring. Trypsin & Chymotrypsin are absorbed into the plasma, and the esterases levels were found to
increase after administration of enzymes.

c. There are reports suggesting modulation of inflammation. They reduce the proinflammatory mediators
and fasten the healing process.

INDICATIONS AND USAGE

Surgery: Post-operative wounds, Oedema & Haematoma, Prevention of inflammation of the stitching.

Gynecology: Pelvic Inflammatory Disease, Caesarean section, Episiotomy, Hysterectomy, D & C.

Dentistry: Tooth Extraction, Periapical abscess, Maxillofacial surgery.

Orthopedics: Post-traumatic edema, soft tissue injury, Fractures & dislocation, Sports injury, Sprains &
Strains, Intervertebral disc herniation.

Ophthalmology: Ocular Trauma such as Macular edema, Black eye, Hyphema, Uveal tract inflammation,
Subconjunctival hemorrhage, Extra —ocular trauma.

ENT: Auricular Septa! hematoma, Nasal fractures, Parapharyngeal abscess.

DOSAGE AND ADMINISTRATION

1 tablet 2 times a day. Treatment should begin as soon as possible after injury occurs.

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