FAIRGEST 200 SR

FAIRGEST-100/200 Injection
Natural Micronized Progesterone 100,200 mg

FAIRGEST Tablets contains micronized progesterone, which is structurally and biologically identical to
progesterone of ovarian origin. Micronisation increases the bioavailability of progesterone. Progesterone is a
21-carbon hormone formed from steroid precursors in the ovary, testis, adrenal gland, placenta, and glial cells
in the central nervous system. Progesterone is present in highest concentrations in the ovarian corpus
luteum. Progesterone receptors are located in the uterus, central nervous system, mammary gland, and
pituitary gland. Progesterone synthesis is stimulated by LH, which primarily acts to regulate the conversion of
cholesterol to pregnenolone, a progesterone precursor.

INDICATIONS

Infertility and Pregnancy
->Luteal support during assisted reproductive techniques (ART)
->To provide luteal support in luteal phase defects
-> Threatened abortion / recurrent abortion with proven luteal phase insufficiency/ defects
-> Oocyte donation programme
-> To prevent preterm delivery
-> Menstrual Irregularities
-> As progesterone challenge test in secondary amenorrhoea
-> Dysfunctional uterine bleeding (DUB)
->Postmenopausal women
-> Prevention of endometrial hyperplasia in non-hysterectomised postmenopausal women who are
receiving estrogen as Hormone Replacement Therapy (HRT)

Premenstrual syndrome

DOSAGE AND ADMINISTRATION

Flexible dosage regimen can be followed depending on the indication and requirements of patients. Lower
dose is required when vaginal route is used.

Vaginal Administration

Each tablet should be inserted deeply into the yagina. Rectal administration should be considered whenever
vaginal administration is not possible.

Luteal support during assisted reproductive techniques (IVF- ET): FAIRGEST 200mg thrice a day
from the day of embryo transfer till pregnancy is confirmed. If pregnant, it is continued till 12th week of
pregnancy.

To provide luteal support in luteal phase defects: FAIRGEST 100 mg thrice a day from the 17th day of the
cycle for 10 days. If pregnant, it is continued tilll2th week of pregnancy.
Threatened abortion / recurrent abortion with proven luteal phase insufficiency/defects: FAIRGEST
100 mg thrice a day till 12th week of pregnancy.

Oocyte donation programme: FAIRGEST 100 mg thrice daily from the day of embryo transfer till pregnancy
is confirmed. If pregnant it is continued till 12th week of pregnancy.
Prevention of preterm delivery: FAIRGEST 100 mg administered once daily at bedtime from 24th to 34th
week of pregnancy.

Oral Administration

The evening dose/once daily dose is preferably taken at bedtime.
-> In secondary amenorrhoea: FAIRGEST 400 mg daily at bedtime for 10 days.
-> Dysfunctional uterine bleeding (DUB): FAIRGEST 300 mg once daily from 12th day of the cycle for 10
days.
-> Postmenopausal women with intact uterus (in addition to estrogen treatment): FAIRGEST 200 mg
at bed time for 12 days sequentially per 28 day cycle.
-> Premenstrual syndrome: FAIRGEST 100-200 mg once daily from 14th day of the cycle for 10 days.

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