AUTOBACT LB

Amoxycillin 1000 mg + Clavulanic Acid 200 mg

Autoclav is a formulation of amoxycillin and clavulanic acid. Amoxycillin has a broad spectrum of bactericidal activity against many gram-positive and gram-negative microorganisms.

Amoxycillin is, however, susceptible to degradation by (beta)-lactamases, and therefore, the spectrum of activity does not include organisms which produce these enzymes.

Clavulanic acid is a (beta)-lactam, structurally related to the penicillins, which possesses the ability to inactivate a wide range of (beta)-lactamase enzymes commonly found in microorganisms resistant to penicillins and cephalosporins. In particular, it has good activity against the clinically important plasmid-mediated (beta)-lactamases frequently responsible for transferred drug resistance.

RATIONALE OF COMBINATION The formulation of amoxycillin and clavulanic acid in Autoclav protects amoxycillin from degradation by (beta)-lactamase enzymes and effectively extends the antibiotic spectrum of amoxycillin to include many bacteria normally resistant to amoxycillin and other (beta)-Iactam antibiotics. Thus, Autoclav possesses the properties of a broad-spectrum antibiotic and a (beta)-lactamase inhibitor.

CLAVULANIC ACID ADVANTAGE:

Retains the activity of amoxicillin against Streptococci including pneumococci

Restores the activity against beta lactamase producing staphylococci, E.coli ,H. influenzae & M. Catarrhalis Extends its activity against Klebsiella spp. & Bacteroides fragilis (which have intrinsic b eta-lactamase production)

INDICATIONS

Autobact is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the conditions listed below:
Lower Respiratory Tract Infections – caused by (beta)-lactamase producing strains of H. influenzae and M.

catarrhalis.

Otitis Media – caused by (beta)-lactamase producing strains of H. influenzae and M. catarrhalis.

Sinusitis – caused by (beta)-Iactamase producing strains of H. influenzae and M. catarrhalis.

Skin and Skin Structure Infections – caused by (beta)-lactamase producing strains of S. aureus, E. coli and

Klebsiella spp.

Urinary Tract Infections – caused by (beta)-lactamase producing strains of E. coli, Klebsiella spp. and

Enterobacter spp.

DOSAGE AND ADMINISTRATION

Autobact Tablets

Adults and Children over 12 years

Usual dosages for the treatment of infection.

Mild to Moderate Infections One 625 mg tablet twice a day.

Autobact Dry Syrup

Usual dosages for the treatment of infection.

Patients aged 12 weeks (3 months) and older.

Mild to Moderate infections 25/3.6 mg/kg/day b.i.d
,Severe Infections and Otitis media, sinusitis, lower.respiratory infections 45/6.4 mg/kgfday b.i.d

USPS OF AUTOBACT TABLETS:

i.) Spectrum of activity against anaerobes and gram negative pathogens
ii.) Drug of Choice in Adults with pneumonia, bronchitis as well as URTIs, SSTIs, UTIs
iii.) Category B drug
iv.) Safe and well tolerated especially in infants and pregnant mothers
v.) Safe during lactation

USPS OF AUTOBACT DRY SYRUP:

i.) THE MOST PALATABLE AND DELICIOUS SYRUP
ii.) 100% compliance
iii.) 100% efficacy in otitis media
iv.) Ensures 95% bacteriological eradication rate
v.) Preferred antibiotic in pediatric…considered as gold standard

  • S.C.F. NO. 377, M.MARKET, MANIMAJRA
  • INFO@BIOFIELDPHARMA.COM
Get Best Pharma Franchise Deals
close slider

Inquire Us